hrp0086p2-p665 | Growth P2 | ESPE2016

Association between IGF-1 (Insulin-Like Growth Factor) SD Levels and Children with Growth Hormone Deficiency with and without Pituitary Morphological Abnormalities

Claudia Schmitt-Lobe Maria , Frare Dionara , Greco Rafael

Background: The diagnostic use of IGF-1 in children suspected of GHD is based on the assumption that a single determination of this parameter reflects the integrated 24-h GH secretion. IGF-1 levels are low in GHD, but a study found a significantly lower sensitivity in children with organic lesions in the brain.Objective: The aim of this study was to check if there is a statistically significant relation between IGF-1 values in children with GHD with and ...